Bocconoline

Names

[ CAS No. ]:
1322007-90-8

[ Name ]:
Bocconoline

Biological Activity

[Description]:

Bocconoline is a potent early endosome antigen 1 (EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[Target]

EEA1[1]

[In Vitro]

Bocconoline (compound 3) (30 μM; 24 h; hONS cells) affects primarily on EEA1 marker intensity in the cytoplasm, mitochondria marker intensity in inner region of the cytoplasm and microtubule-associated protein light chain 3B (LC3b) marker intensity in inner region of cytoplasm[1].

[References]

[1]. Nguyen DT, et al. Chemical constituents from Macleaya cordata (Willd) R. Br. and their phenotypic functions against a Parkinson's disease patient-derived cell line. Bioorg Med Chem. 2020 Nov 1;28(21):115732.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₁NO₅

[ Molecular Weight ]:
379.41

Bocconoline

Names

Biological Activity

Chemical & Physical Properties

Related Compounds