Neoeriocitrin

Names

[ Name ]:
Neoeriocitrin

[Synonym ]:
(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5-hydroxy-2,3-dihydrochromen-4-one
Neoeriocitrin
EINECS 236-215-3

Biological Activity

[Description]:

Neoeriocitrin, isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor[1][2].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Li L, et al. Comparison of neoeriocitrin and naringin on proliferation and osteogenic differentiation in MC3T3-E1. Phytomedicine. 2011 Aug 15;18(11):985-9.

[2]. Liu C, et al. Extraction and Isolation of Acetylcholinesterase Inhibitors from Citrus limon Peel Using an in vitro Method. J Sep Sci. 2020 Jan 30.

Chemical & Physical Properties

[ Density]:
1.73g/cm3

[ Boiling Point ]:
960.7ºC at 760 mmHg

[ Melting Point ]:
277ºC

[ Molecular Formula ]:
C₂₇H₃₂O₁₅

[ Molecular Weight ]:
596.53400

[ Flash Point ]:
318.3ºC

[ Exact Mass ]:
596.17400

[ PSA ]:
245.29000

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.727

[ Water Solubility ]:
Very slightly soluble (0.27 g/L) (25 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Identification of the effective constituents for anti-inflammatory activity of Ju-Zhi-Jiang-Tang, an ancient traditional Chinese medicine formula.

J. Chromatogr. A. 1348 , 105-24, (2014)

The anti-inflammatory constituents of Ju-Zhi-Jiang-Tang (JZJT), a formula used for thousands of years in China, were identified by LC-MS and pharmacological activity evaluation. In this study, the who...