Fmoc-Tle-OH

Names

[ Name ]:
Fmoc-Tle-OH

[Synonym ]:
Fmoc-L-tert-leucine
Fmoc-tBu-Gly-OH
L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-methyl-
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-methyl-L-valine
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-dimethylbutanoic acid
MFCD00065649
Fmoc-Tle-OH

Biological Activity

[Description]:

Fmoc-Tle-OH is a leucine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
554.1±33.0 °C at 760 mmHg

[ Melting Point ]:
124-127 °C

[ Molecular Formula ]:
C₂₁H₂₃NO₄

[ Molecular Weight ]:
353.412

[ Flash Point ]:
288.9±25.4 °C

[ Exact Mass ]:
353.162720

[ PSA ]:
75.63000

[ LogP ]:
4.77

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.584

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%