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BPR1J-097

Names

[ CAS No. ]:
1327167-19-0

[ Name ]:
BPR1J-097

[Synonym ]:
BPR1J-097

Biological Activity

[Description]:

BPR1J-097 is a novel potent FLT3 inhibitor with an IC50 of 11 nM.

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3

Research Areas >> Cancer

[References]

[1]. Lin WH, et al. BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML. Br J Cancer. 2012 Jan 31;106(3):475-81.

[Related Small Molecules]

Gilteritinib | Quizartinib (AC220) | Pacritinib | Linifanib (ABT-869) | LY2784544 | DCC-2036 (Rebastinib) | Dovitinib (TKI-258, CHIR-258) | SB1317 | mrx-6313 | CHIR-124 | KW-2449 | ENMD-2076 | AST 487 | Tandutinib (MLN518) | TG101209

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₈N₆O₃S

[ Molecular Weight ]:
516.61500

[ Exact Mass ]:
516.19400

[ PSA ]:
118.81000

[ LogP ]:
5.11130

[ Storage condition ]:
-20℃

Related Compounds