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m-PEG16-alcohol

Names

[ CAS No. ]:
133604-58-7

[ Name ]:
m-PEG16-alcohol

[Synonym ]:
MeO-16eg-OH
hexadecaethylene glycol monomethyl ether
hexadecylethylene glycol monomethylether
2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-Hexadecaoxanonatetracontan-49-ol

Biological Activity

[Description]:

m-PEG16-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Du JZ, et al. Micelle-to-vesicle morphological transition via light-induced rapid hydrophilic arm detachment from a star polymer. Chem Commun (Camb). 2012 Jan 30;48(9):1257-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H68O17

[ Molecular Weight ]:
736.88300

[ Exact Mass ]:
736.44600

[ PSA ]:
167.91000

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds