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PF9601N

Names

[ CAS No. ]:
133845-63-3

[ Name ]:
PF9601N

[Synonym ]:
PF9601N
N-(2-propynyl)-(5-benzyloxy-2-indolyl)methylamine

Biological Activity

[Description]:

PF9601N, an monoamine oxidase B (MAO-B) inhibitor, possesses neuroprotective properties in several in vitro and in vivo models of Parkinson's disease (PD). PF9601N can be used for the research of neurodegenerative diseases mediated by excitotoxicity[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase
Research Areas >> Neurological Disease

[References]

[1]. Irene Bolea, et al. Neuroprotective effects of the MAO-B inhibitor, PF9601N, in an in vivo model of excitotoxicity. CNS Neurosci Ther. 2014 Jul;20(7):641-50.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H18N2O

[ Molecular Weight ]:
290.35900

[ Exact Mass ]:
290.14200

[ PSA ]:
37.05000

[ LogP ]:
3.86060

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Related Compounds