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Lipoamido-PEG3-OH

Names

[ CAS No. ]:
1342764-64-0

[ Name ]:
Lipoamido-PEG3-OH

[Synonym ]:
LIPOAMIDO-PEG3-OH

Biological Activity

[Description]:

Lipoamido-PEG3-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG3-OH (compound TA-TEG-G2CN) can be used in the formation of a highly stable, dendronized gold nanoparticle (AuNP)-based drug delivery platform[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. Saha Ray A,et al. Set of Highly Stable Amine- and Carboxylate-Terminated Dendronized Au Nanoparticles with Dense Coating and Nontoxic Mixed-Dendronized Form.Langmuir. 2019 Mar 5;35(9):3391-3403.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
573.8±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H31NO5S2

[ Molecular Weight ]:
381.551

[ Flash Point ]:
300.8±27.3 °C

[ Exact Mass ]:
381.164368

[ LogP ]:
0.12

[ Vapour Pressure ]:
0.0±3.6 mmHg at 25°C

[ Index of Refraction ]:
1.524

[ Storage condition ]:
2-8°C

Related Compounds