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G-744

Names

[ CAS No. ]:
1346669-54-2

[ Name ]:
G-744

Biological Activity

[Description]:

G-744 is a highly potent, selective Btk inhibitor with an IC50 of 2 nM.

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

[Target]

IC50: 2 nM (Btk)[1]

[References]

[1]. Wang X, et al. Discovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties. ACS Med Chem Lett. 2017 May 3;8(6):608-613.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds