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Lamivudine

Names

[ CAS No. ]:
134678-17-4

[ Name ]:
Lamivudine

[Synonym ]:
2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
3TC
Heptodin
cent
(-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
Lamivudine
Zeffix
Zefix
Hepitec
Heptivir
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S)
2',3'-Dideoxy-3'-thiacytidine
Heptovir
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
MFCD00869739
(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cystosine
4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
Epivir
4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
3&L-SddC

Biological Activity

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
475.4±55.0 °C at 760 mmHg

[ Melting Point ]:
177 °C

[ Molecular Formula ]:
C8H11N3O3S

[ Molecular Weight ]:
229.256

[ Flash Point ]:
241.3±31.5 °C

[ Exact Mass ]:
229.052109

[ PSA ]:
115.67000

[ LogP ]:
-0.71

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.755

[ Storage condition ]:
Freezer

MSDS

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H361

[ Precautionary Statements ]:
P281

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
63

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
UW7361333

[ HS Code ]:
2934999090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2938901000

[ Summary ]:
HS: 2938901000. 4-amino-1-((2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1h)-one. VAT:17.0%. tax rebate rate:13.0%. supervision conditions:None. MFN tarrif:6.5%. general tariff:20.0%

Articles

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This study characterized the kinetics, variability, and factors that affect UDP-glucuronic acid (UDP-GlcUA) uptake by human liver microsomes (HLM). Biphasic kinetics were observed for UDP-GlcUA uptake...

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Anal. Bioanal. Chem 407(8) , 2073-84, (2015)

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The stress response resolution assay. I. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium.

Environ. Mol. Mutagen. 54(4) , 268-80, (2013)

The events or factors that lead from normal cell function to conditions and diseases such as aging or cancer reflect complex interactions between cells and their environment. Cellular stress responses...


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Related Compounds