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Nav1.7 inhibitor

Names

[ CAS No. ]:
1355631-24-1

[ Name ]:
Nav1.7 inhibitor

[Synonym ]:
Nav1.7 inhibitor

Biological Activity

[Description]:

Nav1.7 inhibitor is a potent Nav1.7 inhibitor.IC50 value:Target: Nav1.7Preparation of sulfonamide derivatives as Nav1.7 inhibitorsBy Brown, Alan Daniel; Rawson, David James; Storer, Robert Ian; Swain, Nigel Alan From PCT Int. Appl. (2012), WO 2012007868 A2 20120119.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel
Research Areas >> Neurological Disease

[References]

[1]. Preparation of sulfonamide derivatives as Nav1.7 inhibitors. Patent WO 2012007868 A2 20120119


[Related Small Molecules]

EIPA | Riluzole | Ginsenoside Rg3 | Cariporide | Eleclazine hydrochloride | GS967 | Tenapanor | Triamterene | Ranolazine dihydrochloride | PF 05089771 | flecainide acetate | A-803467 | CNV1014802 (hydrochloride) | Zonisamide | Cinchocaine

Chemical & Physical Properties

[ Molecular Formula ]:
C15H11Cl3FNO4S

[ Molecular Weight ]:
426.67500

[ Exact Mass ]:
424.94600

[ PSA ]:
84.34000

[ LogP ]:
5.70990

[ Storage condition ]:
2-8℃

Related Compounds