QCC-374

Names

[ Name ]:
QCC-374

[Synonym ]:
7-[2,3-Bis(4-methylphenyl)-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl]heptanoic acid
Pyrido[2,3-b]pyrazine-5(6H)-heptanoic acid, 7,8-dihydro-2,3-bis(4-methylphenyl)-
7,8-Dihydro-2,3-bis(4-methylphenyl)pyrido[2,3-b]pyrazine-5(6H)-heptanoic acid

Biological Activity

[Description]:

QCC374 is a selective agonist of IP[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

[References]

[1]. Zheng W, et al. Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives. J Med Chem. 2020 Dec 24;63(24):15153-15186.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
620.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₈H₃₃N₃O₂

[ Molecular Weight ]:
443.58

[ Flash Point ]:
329.1±31.5 °C

[ Exact Mass ]:
443.257263

[ LogP ]:
7.05

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.584

[ Storage condition ]:
-20℃

QCC-374

Names

Biological Activity

Chemical & Physical Properties

Related Compounds