1,4-Dihydro-4-oxoquinoline-2-carboxylic acid

Names

[ CAS No. ]:
13593-94-7

[ Name ]:
1,4-Dihydro-4-oxoquinoline-2-carboxylic acid

[Synonym ]:
4-Oxo-1,4-dihydroquinoline-2-carboxylic acid
1,4-Dihydro-4-oxoquinoline-2-carboxylic acid

Biological Activity

[Description]:

Transtorine is a quinoline alkaloid, found from Ephedra transitoria, with antibacterial activity[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Transtorine shows growth inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Enterobacter cloacae, with MIC 0.38, 0.5, and 0.45 mg/mL, respectively[1].

Chemical & Physical Properties

[ Density]:
1.429g/cm3

[ Boiling Point ]:
358.4ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₇NO₃

[ Molecular Weight ]:
189.16700

[ Flash Point ]:
170.5ºC

[ Exact Mass ]:
189.04300

[ PSA ]:
70.16000

[ LogP ]:
1.22630

MSDS

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Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933499090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%