RTC13
Names
[ CAS No. ]:
1359825-94-7
[ Name ]:
RTC13
[Synonym ]:
(5Z)-2-Amino-5-[[5-(2-nitrophenyl)-2-furanyl]methylene]-4(5H)-thiazolone
(Z)-2-amino-5-((5-(2-nitrophenyl)furan-2-yl)methylene)thiazol-4(5H)-one
4(5H)-Thiazolone, 2-amino-5-[[5-(2-nitrophenyl)-2-furanyl]methylene]-, (5Z)-
Biological Activity
[Description]:
RTC13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy (DMD)[1].
[Related Catalog]:
[In Vivo]
Animal Model: Wild-type (C57BL/10) mice at 10 to 12 weeks of age[1]. Dosage: 10 (n = 5), 30 (n = 5), 60 (n = 5) or 300 mg/kg (n = 5). Administration: Intraperitoneal Administration. Result: No changes were observed in liver and kidney weights at the time of necropsies, and Hematoxylin and Eosin (H&E) staining revealed the absence of histopathological changes.
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C14H9N3O4S
[ Molecular Weight ]:
315.30
[ Exact Mass ]:
315.03100
[ PSA ]:
139.71000
[ LogP ]:
3.44290