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PACAP (6-27) (human, ovine, rat)

Names

[ CAS No. ]:
136134-68-4

[ Name ]:
PACAP (6-27) (human, ovine, rat)

[Synonym ]:
PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE AMIDE FRAGMENT 6-27

Biological Activity

[Description]:

PACAP (6-27) (human, ovine, rat) is a PACAP receptor antagonist that blocks the canine adrenal catecholamine response to exogenous vasoactive intestinal peptide (VIP). PACAP (6-27) (human, ovine, rat) has the potential to study cardiovascular and neurological diseases[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adenylate Cyclase
Research Areas >> Neurological Disease

[Target]

PACAP receptor[1].


[References]

[1]. Gaspo R, et al. Canine adrenal catecholamine response to VIP is blocked by PACAP-(6-27) in vivo. Am J Physiol. 1997 May;272(5 Pt 2):R1606-12.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
1561.8±75.0 °C at 760 mmHg

[ Molecular Formula ]:
C121H193N33O31S

[ Molecular Weight ]:
2638.09

[ Flash Point ]:
898.4±37.1 °C

[ Exact Mass ]:
1550.766357

[ LogP ]:
6.42

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.665

[ Storage condition ]:
−20°C

Safety Information

[ WGK Germany ]:
3


Related Compounds