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6-O-Caffeoylarbutin

Names

[ CAS No. ]:
136172-60-6

[ Name ]:
6-O-Caffeoylarbutin

[Synonym ]:
4-Hydroxyphenyl 6-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside
β-D-Glucopyranoside, 4-hydroxyphenyl 6-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]-
p-hydroxy-phenoxyacetic acid
Hydrochinon-mono-glykolsaeure
robustaside B
4-Hydroxypheoxyacetate
6-O-caffeoylarbutin

Biological Activity

[Description]:

6-O-Caffeoylarbutin (Robustaside B) possesses antioxidant activity[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[In Vitro]

In the presence of calcium, similar concentrations of robustaside B decreases the extentof MPT pore opening in a concentration-dependent manner but in the reverse order[1]. Robustaside B (0.1mM) and para-hydroxyphenol(0.05mM) significantly inhibits mitochondrial lipid peroxidation induced by the Fe2+/ascorbate system by causing a significant decrease (86.4 and 86.7%), respectively, in the amount of TBARS released by the system[1].

[References]

[1]. Rahmat A Adisa, et al. Robustaside B and para‑hydroxyphenol: phenolic and antioxidant compounds purified from Cnestis ferruginea D.C induced membrane permeability transition in rat liver mitochondria. Mol Med Rep. 2013 Nov;8(5):1493-8.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
769.8±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H22O10

[ Molecular Weight ]:
434.393

[ Flash Point ]:
271.6±26.4 °C

[ Exact Mass ]:
434.121307

[ PSA ]:
166.14000

[ LogP ]:
1.43

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.699

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds