Fendiline Hydrochloride

Names

[ CAS No. ]:
13636-18-5

[ Name ]:
Fendiline Hydrochloride

[Synonym ]:
Fendiline hydrochloride
Fendiline (hydrochloride)

Biological Activity

[Description]:

Fendiline is a nonselective calcium channel blocker.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Cardiovascular Disease

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.031g/cm3

[ Boiling Point ]:
452.1ºC at 760mmHg

[ Molecular Formula ]:
C₂₃H₂₆ClN

[ Molecular Weight ]:
351.91200

[ Flash Point ]:
207.9ºC

[ Exact Mass ]:
351.17500

[ PSA ]:
12.03000

[ LogP ]:
6.75230

[ Vapour Pressure ]:
2.3E-08mmHg at 25°C

[ Storage condition ]:
-20℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DP4790000

CHEMICAL NAME :: Benzylamine, N-(3,3-diphenylpropyl)-alpha-methyl-, hydrochloride

CAS REGISTRY NUMBER :: 13636-18-5

LAST UPDATED :: 199601

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C23-H25-N.Cl-H

MOLECULAR WEIGHT :: 351.95

WISWESSER LINE NOTATION :: 1YR&M2YR&R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 950 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3262977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3262977

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DP4790000

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