BETP
Names
[ CAS No. ]:
1371569-69-5
[ Name ]:
BETP
[Synonym ]:
4-(3-(benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine
4-(3-benzyloxyphenyl)-2-ethylsulfinyl-6-(trifluoromethyl)pyrimidine
Biological Activity
[Description]:
[Related Catalog]:
[Target]
EC50: 0.66 μM (Human GLP-1 receptor), 0.755 μM (Rat GLP-1 receptor)[1]
[In Vitro]
[In Vivo]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Molecular Formula ]:
C20H17F3N2O2S
[ Molecular Weight ]:
406.42100
[ Exact Mass ]:
406.09600
[ PSA ]:
71.29000
[ LogP ]:
5.73460
[ Storage condition ]:
2-8°C
Safety Information
[ RIDADR ]:
NONH for all modes of transport
Articles
Br. J. Pharmacol. 171(15) , 3651-65, (2014)
The glucagon-like peptide 1 (GLP-1) receptor performs an important role in glycaemic control, stimulating the release of insulin. It is an attractive target for treating type 2 diabetes. Recently, sev...