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Odiparcil

Names

[ CAS No. ]:
137215-12-4

[ Name ]:
Odiparcil

Biological Activity

[Description]:

Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events. Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) [1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> Thrombin

[Target]

Thrombin[2]


[References]

[1]. Myers AL, et al. Characterization of total plasma glycosaminoglycan levels in healthy volunteers following oral administration of a novel antithrombotic odiparcil with aspirin or enoxaparin. J Clin Pharmacol. 2008 Oct;48(10):1158-70

[2]. Levy JH, et al. Novel oral anticoagulants: implications in the perioperative setting. Anesthesiology. 2010 Sep;113(3):726-45.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H16O6S

[ Molecular Weight ]:
324.34900

[ Exact Mass ]:
324.06700

[ PSA ]:
125.43000

[ LogP ]:
0.63580

[ Vapour Pressure ]:
1.03E-13mmHg at 25°C

Related Compounds