2,3-diphosphonooxypropanoic acid

Names

[ CAS No. ]:
138-81-8

[ Name ]:
2,3-diphosphonooxypropanoic acid

[Synonym ]:
2,3-Diphospho-D-glyceric acid
2,3-bis-phosphonooxy-propionic acid
2,3-Diphosphoglycerate
2,3-Dpg
2,3-diphosphonooxypropanoic acid
di-phospho-glycerate
D-glyceric acid bisphosphate
2,3-Bisphosphoglycerate
2,3-Bis-phosphonooxy-propionsaeure
Glycerinsaeure-2,3-diphosphat
Diphoshate glyceric acid
2,3-Diphosphoglyceric acid

Biological Activity

[Description]:

2,3-Diphosphoglyceric acid (2,3-DPG) is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2,3-Diphosphoglyceric acid binds to hemoglobin and decrease its affinity for oxygen[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Shakil H. Merchant MD, et al. 24 - Molecular Diagnosis in Hematopathology. Hematopathology (Second Edition).2012, 679-726.

[2]. Płoszczyca K, et al. Red Blood Cell 2,3-Diphosphoglycerate Decreases in Response to a 30 km Time Trial Under Hypoxia in Cyclists. Front Physiol. 2021 Jun 15;12:670977.

Chemical & Physical Properties

[ Density]:
2.143g/cm3

[ Boiling Point ]:
669.8ºC at 760mmHg

[ Molecular Formula ]:
C₃H₈O₁₀P₂

[ Molecular Weight ]:
266.03700

[ Flash Point ]:
358.9ºC

[ Exact Mass ]:
265.95900

[ PSA ]:
190.44000

Safety Information

[ HS Code ]:
2931900090

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%