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Coronarin D ethyl ether

Names

[ CAS No. ]:
138965-89-6

[ Name ]:
Coronarin D ethyl ether

[Synonym ]:
coronarin-D ethyl ether
2(3H)-Furanone, 3-[2-[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]ethylidene]-5-ethoxydihydro-, (3E)-
coronarin B
(3E)-5-Ethoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone

Biological Activity

[Description]:

Ethoxycoronarin D is a labdane diterpenes compound isolated from rhizomes. Ethoxycoronarin D selectively inhibits COX-1 with an IC50 of 3.8 µM[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. Denise C. Endringer, et al. Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
460.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H34O3

[ Molecular Weight ]:
346.504

[ Flash Point ]:
197.8±23.3 °C

[ Exact Mass ]:
346.250793

[ PSA ]:
35.53000

[ LogP ]:
6.18

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.515

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds