Furaltadone
Names
[ CAS No. ]:
139-91-3
[ Name ]:
Furaltadone
[Synonym ]:
Furmethonol
Furaltadone
2-oxazolidinone, 5-(4-morpholinylmethyl)-3-[[(5-nitro-2-furanyl)methylene]amino]-
Altabactina
Furazolin
nf260
Darifur
Sepsinol
Medifuran
ibifur
MFCD00057356
5-morpholin-4-ylmethyl-3-(5-nitro-furan-2-ylmethyleneamino)-oxazolidin-2-one
Nitrofurmethone
f-150
5-morpholinomethyl-3-(5-nitro-furfurylidenamino)-oxazolidin-2-one
3-(5-Nitro-2-furfurylideneamino)-5-(4-morpholinomethyl)-2-oxazolidone
Altafur
EINECS 205-384-5
Nitraldone
5-(Morpholinomethyl)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-one
5-(morpholin-4-ylmethyl)-3-{[(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one
5-Morpholinomethyl-3-(5-nitro-furfurylidenamino)-oxazolidin-2-on
2-Oxazolidinone, 5-(4-morpholinylmethyl)-3-[[(1E)-(5-nitro-2-furanyl)methylene]amino]-
Otifuril
5-(Morpholin-4-ylmethyl)-3-{[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one
5-(4-morpholinomethyl)-3-(5-nitro-2-furfurylideneamino)-2-oxazolidinone
Unifur
5-Morpholinomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidinone
5-(4-Morpholinylmethyl)-3-{(E)-[(E)-(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one
Ultrafur
VALSYN
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
461.4±55.0 °C at 760 mmHg
[ Melting Point ]:
206ºC (dec.)
[ Molecular Formula ]:
C13H16N4O6
[ Molecular Weight ]:
324.289
[ Flash Point ]:
232.8±31.5 °C
[ Exact Mass ]:
324.106995
[ PSA ]:
113.33000
[ LogP ]:
-0.84
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.669
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RQ3620000
- CHEMICAL NAME :
- 2-Oxazolidinone, 5-(morpholinomethyl)-3-((5-nitrofurfurylidene)amino)-
- CAS REGISTRY NUMBER :
- 139-91-3
- BEILSTEIN REFERENCE NO. :
- 0363627
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C13-H16-N4-O6
- MOLECULAR WEIGHT :
- 324.33
- WISWESSER LINE NOTATION :
- T5OJ BNW E1UN- AT5NVOTJ D1- AT6N DOTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - antipsychotic Lungs, Thorax, or Respiration - respiratory depression Kidney, Ureter, Bladder - other changes in urine composition
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Microorganism - not otherwise specified
- DOSE/DURATION :
- 5 mg/L
- REFERENCE :
- CUMIDD Current Microbiology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1978- Volume(issue)/page/year: 10,19,1984
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
3-26
[ RIDADR ]:
UN 3249
[ WGK Germany ]:
3
[ RTECS ]:
RQ3620000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2934992000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Antimicrob. Agents Chemother. 57(4) , 1603-9, (2013)
RarA is an AraC-type regulator in Klebsiella pneumoniae, which, when overexpressed, confers a low-level multidrug-resistant (MDR) phenotype linked to the upregulation of both the acrAB and oqxAB efflu...
Development of a competitive ELISA for the detection of a furaltadone marker residue, 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), in cultured fish samples.J. Vet. Med. Sci. 74(11) , 1439-46, (2012)
This report describes an enzyme-linked immunosorbent assay (ELISA) for tissue-bound metabolite 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ) and the application to residue analysis in cultured fis...
Cloning, expression, purification, and characterization of a novel single-chain variable fragment antibody against the 2-nitrobenzaldehyde derivative of a furaltadone metabolite in Escherichia coli.Protein Expr. Purif. 84(1) , 140-6, (2012)
Furaltadone is an illicit veterinary drug that shows toxic, carcinogenic, and mutagenic effects, as does its metabolite 3-amino-5-morpholinomethyl-2-oxazolidone (AMOZ)(1). Recombinant antibodies with ...