Carmine

Names

[ Name ]:
Carmine

[Synonym ]:
(1S)-1,5-Anhydro-1-(7-carboxy-1,3,4,6-tetrahydroxy-8-methyl-9,10-dioxo-9,10-dihydro-2-anthracenyl)-D-glucitol
D-Glucitol, 1,5-anhydro-1-C-(7-carboxy-9,10-dihydro-1,3,4,6-tetrahydroxy-8-methyl-9,10-dioxo-2-anthracenyl)-, (1S)-
Carmine,high purity biol.stain,alum lake of carminic acid
MFCD00167028
Carmine Red
Broseliquid
rougerecd
EINECS 215-724-4
Carmine,certified,alum lake of carminic acid
Alum lake of carminic acid,Cochineal,Nacarat
2-Anthracenecarboxylic acid, 7-β-D-glucopyranosyl-9,10-dihydro-3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-
(1S)-1,5-Anhydro-1-(7-carboxy-1,3,4,6-tetrahydroxy-8-methyl-9,10-dioxo-9,10-dihydroanthracen-2-yl)-D-glucitol
CARMINIC ACID

Biological Activity

[Description]:

Carmine (Carmine red), a "semi-synthetic" dye, is a complex of aluminum and the natural dye Cochineal (Carminic acid). Cochineal is isolated from the native Mexican and South American insect. Carmine is a widely used "natural" food additive. Carmine provokes both an immediate hypersensitivity and a delayed systemic response with cutaneous expression[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[In Vitro]

Carmine has been used in biological staining to demonstrate selectively nuclei, chromosomes or mucins, depending on the formulation[2].

[References]

[1]. Chandler W Rundle, et al. Contact Dermatitis to Carmine. Dermatitis. Sep/Oct 2018;29(5):244-249.

[2]. R W Dapson, et al. The history, chemistry and modes of action of carmine and related dyes. Biotech Histochem. 2007 Aug;82(4-5):173-87.

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
907.6±65.0 °C at 760 mmHg

[ Melting Point ]:
136ºC dec

[ Molecular Formula ]:
C₂₂H₂₀O₁₃

[ Molecular Weight ]:
492.386

[ Flash Point ]:
316.1±27.8 °C

[ Exact Mass ]:
492.090393

[ PSA ]:
256.66000

[ LogP ]:
4.80

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.792

[ Storage condition ]:
Store at +5°C to +30°C.

[ Water Solubility ]:
ammonium hydroxide: soluble1mg/mL

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FH8891000

CHEMICAL NAME :: Carmine

CAS REGISTRY NUMBER :: 1390-65-4

LAST UPDATED :: 199504

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T+

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
FH8891000

Articles

A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development.

Oncogene 34 , 4777-90, (2015)

Breast cancer is a major cause of mortality in women. The transcription factor SNAI2 has been implicated in the pathogenesis of several types of cancer, including breast cancer of basal origin. Here w...

Transcriptome analysis of the hormone-sensing cells in mammary epithelial reveals dynamic changes in early pregnancy.

BMC Dev. Biol. 15 , 7, (2015)

Alveoli, the milk-producing units of the mammary gland, are generated during pregnancy by collaboration of different epithelial cell types. We present the first analysis of transcriptional changes wit...

Analysis and testing of biological stains--the Biological Stain Commission Procedures.

Biotech. Histochem. 77(5&6) , 237-275, (2002)