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RIP2 Kinase Inhibitor 3

Names

[ CAS No. ]:
1398053-50-3

[ Name ]:
RIP2 Kinase Inhibitor 3

Biological Activity

[Description]:

RIP2 Kinase Inhibitor 3 is a highly potent and selective inhibitor of receptor interacting protein-2 (RIP2) Kinase with an IC50 of 1 nM [1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> RIP kinase

Research Areas >> Inflammation/Immunology

[Target]

IC50: 1 nM (RIP2)[1]

[References]

[1]. Haile PA, et al. Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel. ACS Med Chem Lett. 2018 Sep 26;9(10):1039-1044.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₄N₄O₃S

[ Molecular Weight ]:
388.48

Related Compounds