4-Chlorobenzyl cyanide
Names
[ CAS No. ]:
140-53-4
[ Name ]:
4-Chlorobenzyl cyanide
[Synonym ]:
4-Chlorobenzyl Cyanide
Benzeneacetonitrile, 4-chloro-
(4-Chlorophenyl)acetonitrile
4-chlorophenylacetonitrile
EINECS 205-418-9
2-(4-chlorophenyl)acetonitrile
MFCD00001918
p-Chlorobenzyl cyanide
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
266.0±0.0 °C at 760 mmHg
[ Melting Point ]:
25-28 °C(lit.)
[ Molecular Formula ]:
C8H6ClN
[ Molecular Weight ]:
151.59
[ Flash Point ]:
107.7±15.4 °C
[ Exact Mass ]:
151.018875
[ PSA ]:
23.79000
[ LogP ]:
2.04
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.549
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AL8250000
- CHEMICAL NAME :
- Acetonitrile, (p-chlorophenyl)-
- CAS REGISTRY NUMBER :
- 140-53-4
- BEILSTEIN REFERENCE NO. :
- 0971171
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C8-H6-Cl-N
- MOLECULAR WEIGHT :
- 151.60
- WISWESSER LINE NOTATION :
- NC1R DG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 14,1325,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 27 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- PCBPBS Pesticide Biochemistry and Physiology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1971- Volume(issue)/page/year: 2,95,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07883 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4034 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 851 (estimated) No. of Female Employees: 187 (estimated)
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H311-H315-H319-H331-H335
[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R23/24/25;R36/37/38
[ Safety Phrases ]:
S26-S36/37/39-S45-S28B
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
AL8250000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
29269095
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2926901000
[ Summary ]:
HS: 2926901000. 2-(4-chlorophenyl)acetonitrile. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tarrif:4.0%. general tariff:11.0%