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(2R,3S)-Chlorpheg

Names

[ CAS No. ]:
140924-23-8

[ Name ]:
(2R,3S)-Chlorpheg

[Synonym ]:
(2R,3S)-Chlorpheg
Pentylenetetrazole

Biological Activity

[Description]:

(2R,3R)-Chlorpheg is a week antagonist of L-homocysteic acid (L-HCA) induced depolarization.(2R,3R)-Chlorpheg also is a weak N-methyl-D-aspartate (NMDA) antagonist[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR
Research Areas >> Neurological Disease
Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[References]

[1]. D J Chalmers, et, al. Differential actions of 3-(4-chlorophenyl) glutamic acid stereoisomers and L-trans-pyrrolidine-2,4-dicarboxylic acid upon L-homocysteic acid- and L-glutamic acid-induced responses from rat spinal motoneurones. Neuropharmacology. 1995, 34, 12.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H12ClNO4

[ Molecular Weight ]:
257.67

[ Exact Mass ]:
257.04500

[ PSA ]:
100.62000

[ LogP ]:
2.01050

Related Compounds