Btk inhibitor 1

Names

[ Name ]:
Btk inhibitor 1

[Synonym ]:
PCI-7503
3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Btk inhibitor 1

Biological Activity

[Description]:

Btk inhibitor 1 is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.IC50 value:Target: BtkFrom PCT Int. Appl. (2012), WO 2012158843 A2 20121122.

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

Research Areas >> Cancer

[References]

[1]. PCT Int. Appl. (2012), WO 2012158843 A2 20121122.

[Related Small Molecules]

Acalabrutinib | GDC-0853 | Evobrutinib | AVL-292 | (±)-Zanubrutinib | ONO-4059 | BMX-IN-1 | GDC-0834 | SNS-062 | RN486 | LFM-A13 | Vecabrutinib | CGI-1746 | BMS-986195 | CNX-774

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₂N₆O

[ Molecular Weight ]:
386.45000

[ Exact Mass ]:
386.18600

[ PSA ]:
90.88000

[ LogP ]:
4.70230

[ Storage condition ]:
2-8℃

Btk inhibitor 1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds