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Evobrutinib

Names

[ CAS No. ]:
1415823-73-2

[ Name ]:
Evobrutinib

[Synonym ]:
UNII:ZA45457L1K
1-[4-({[6-Amino-5-(4-phenoxyphenyl)-4-pyrimidinyl]amino}methyl)-1-piperidinyl]-2-propen-1-one
2-Propen-1-one, 1-[4-[[[6-amino-5-(4-phenoxyphenyl)-4-pyrimidinyl]amino]methyl]-1-piperidinyl]-
evobrutinib

Biological Activity

[Description]:

Evobrutinib is an inhibitor of Bruton's tyrosin kinase (Btk) inhibitor extracted from patent US20140162983 example 0174.

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
Research Areas >> Cancer

[Related Small Molecules]

Acalabrutinib | GDC-0853 | AVL-292 | (±)-Zanubrutinib | ONO-4059 | BMX-IN-1 | GDC-0834 | SNS-062 | RN486 | LFM-A13 | Vecabrutinib | CGI-1746 | BMS-986195 | CNX-774 | PRN 1008

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
683.4±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C25H27N5O2

[ Molecular Weight ]:
429.514

[ Flash Point ]:
367.1±31.5 °C

[ Exact Mass ]:
429.216461

[ LogP ]:
3.19

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.637

Related Compounds