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GSK2795039

Names

[ CAS No. ]:
1415925-18-6

[ Name ]:
GSK2795039

[Synonym ]:
1H-Pyrazole-3-sulfonamide, N-[3-(2,3-dihydro-1-methyl-1H-indol-6-yl)-1-(1-methylethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-
N-[1-Isopropyl-3-(1-methyl-2,3-dihydro-1H-indol-6-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1H-pyrazole-3-sulfonamide

Biological Activity

[Description]:

GSK2795039 is a NADPH oxidase 2 inhibitor with a mean pIC50 of 6 in different cell-free assays.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cancer

[References]

[1]. Hirano K et al. Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor. Antioxid Redox Signal. 2015 Aug 10;23(5):358-74.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline | BPTES

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
691.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H26N6O2S

[ Molecular Weight ]:
450.556

[ Flash Point ]:
372.0±34.3 °C

[ Exact Mass ]:
450.183807

[ LogP ]:
3.90

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.707

[ Storage condition ]:
2-8℃

Related Compounds