Mutant IDH1-IN-4

Names

[ Name ]:
Mutant IDH1-IN-4

Biological Activity

[Description]:

Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH)

[Target]

IC50: ≤ 0.5 μM (mutant IDH 1 in cells)[1].

[References]

[1]. US20170210749A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₃₄N₄O₃

[ Molecular Weight ]:
438.56246

Mutant IDH1-IN-4

Names

Biological Activity

Chemical & Physical Properties

Related Compounds