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GB-88

Names

[ CAS No. ]:
1416435-96-5

[ Name ]:
GB-88

Biological Activity

[Description]:

GB-88 is a selective, orally PAR2 antagonist, inhibits PAR2 activates Ca(2+) release with an IC 50 of 2 µM[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Protease-Activated Receptor (PAR)
Research Areas >> Inflammation/Immunology

[Target]

PAR2[1]


[References]

[1]. Suen JY, et al. Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110). Br J Pharmacol. 2012 Mar;165(5):1413-23.

Chemical & Physical Properties

[ Molecular Formula ]:
C32H42N4O4

[ Molecular Weight ]:
546.70

[ Storage condition ]:
-20°C


Related Compounds