Cilofexor

Names

[ Name ]:
Cilofexor

[Synonym ]:
2-[3-(2-Chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxy-1-azetidinyl]isonicotinic acid
4-Pyridinecarboxylic acid, 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-
Cilofexor

Biological Activity

[Description]:

Cilofexor is a farnesoid X receptor (FXR) agonist.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> FXR

Research Areas >> Others

[Target]

FXR[1].

[References]

[1]. US9820979B2.

[Related Small Molecules]

Obeticholic acid | GW4064 | T0901317 | Tropifexor | INT-767 | Fexaramine | Chenodeoxycholic acid | XL335 | Androsterone | PX20606 trans racemate | BAR502 | LY2562175

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
855.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₈H₂₂Cl₃N₃O₅

[ Molecular Weight ]:
586.850

[ Flash Point ]:
471.2±34.3 °C

[ Exact Mass ]:
585.062500

[ LogP ]:
4.98

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.689

[ Storage condition ]:
2-8℃