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UNC-1079

Names

[ CAS No. ]:
1418741-86-2

[ Name ]:
UNC-1079

[Synonym ]:
Methanone, 1,1'-(1,4-phenylene)bis[1-[1,4'-bipiperidin]-1'-yl-
1,4-Phenylenebis(1,4'-bipiperidin-1'-ylmethanone)
UNC-1079
UNC1079

Biological Activity

[Description]:

UNC1079 is the piperidine analog of UNC1021, as a structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies. Target: L3MBTL3The low anticipated affinity of UNC1079 was confirmed, as it demonstrated an activity versus L3MBTL3 of > 10 μM by AlphaScreen, which is >1000-fold weaker than UNC1215. UNC1079 also displays weak binding by ITC.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cancer

[References]

[1]. James LI, et al. Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol. 2013 Mar;9(3):184-91.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
640.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C28H42N4O2

[ Molecular Weight ]:
466.659

[ Flash Point ]:
264.2±23.9 °C

[ Exact Mass ]:
466.330780

[ LogP ]:
2.28

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.590

[ Storage condition ]:
2-8℃

Related Compounds