Fluorobenzene

Names

[ Name ]:
Fluorobenzene

[Synonym ]:
Monofluorobenzene
EINECS 215-831-6
DE825
perdeuteriofluorobenzene
1-fluorobenzene
MFCD00000281
Fluorobenzene
d5-fluorobenzene
BENZENYL FLUORIDE
Fluorobenzene [UN2387] [Flammable liquid]
Benzene, fluoro-
Fluorobenzene-d5
pentadeuterio-fluoro-benzene

Biological Activity

[Description]:

Fluorobenzene-d5 is the deuterium labeled Fluorobenzene-d5[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
84.7±9.0 °C at 760 mmHg

[ Melting Point ]:
-42ºC

[ Molecular Formula ]:
C₆D₅F

[ Molecular Weight ]:
96.102

[ Flash Point ]:
-12.8±0.0 °C

[ Exact Mass ]:
96.037529

[ LogP ]:
2.27

[ Vapour Pressure ]:
79.9±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.473

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H315-H319-H335

[ Precautionary Statements ]:
P210-P261-P305 + P351 + P338

[ Hazard Codes ]:
F: Flammable;Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
16-26-36

[ RIDADR ]:
UN 2387

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Vibrations of the S1 state of fluorobenzene-h5 and fluorobenzene-d5 via resonance-enhanced multiphoton ionization (REMPI) spectroscopy.

J. Chem. Phys. 141(24) , 244315, (2014)

We report resonance-enhanced multiphoton ionization spectra of the isotopologues fluorobenzene-h5 and fluorobenzene-d5. By making use of quantum chemical calculations, the changes in the wavenumber of...

The Fokker-Planck-Langevin model for rotational brownian motion. V. Comparison with magnetic relaxation data for asymmetric top molecules. Lee DH and McClung RED.

J. Magn. Reson. 73(1) , 34-44, (1969)

Molecular motions of fluorobenzene-d₅ in the dense fluid region. DeZwaan J, et al.

J. Chem. Phys. 60(8) , 3223-3230, (1974)