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Nicardipine D3 hydrochloride

Names

[ CAS No. ]:
1432061-50-1

[ Name ]:
Nicardipine D3 hydrochloride

[Synonym ]:
2-{Benzyl[(2H3)methyl]amino}ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate hydrochloride (1:1)
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-[methyl-d3(phenylmethyl)amino]ethyl ester, hydrochloride (1:1)

Biological Activity

[Description]:

Nicardipine D3 hydrochloride (YC-93 D3) is the deuterium labeled Nicardipine hydrochloride. Nicardipine hydrochloride is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel
Research Areas >> Neurological Disease

[References]

[1]. Charnet P, et al. Electrophysiological analysis of the action of nifedipine and nicardipine on myocardial fibers. Fundam Clin Pharmacol. 1987;1(6):413-31.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H27D3ClN3O6

[ Molecular Weight ]:
519.004

[ Exact Mass ]:
518.201172


Related Compounds