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merodantoin

Names

[ CAS No. ]:
143413-73-4

[ Name ]:
merodantoin

[Synonym ]:
1,3-Dibutyl-2-thioxo-4,5-imidazolidinedione
4,5-Imidazolidinedione,1,3-dibutyl-2-thioxo
N,N'-Dibutyl-2-thio-4,5-imidazolidion
Merodantoin

Biological Activity

[Description]:

Merodantoin has significant antitumor activity in vitro and in vivo, and has less toxicity to normal cells and tissues[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Gulliya KS, et al. Topoisomerase II-dependent novel antitumor compounds merocil and merodantoin induce apoptosis in Daudi cells. Anticancer Drugs. 1994 Oct;5(5):557-66.  

Chemical & Physical Properties

[ Density]:
1.18g/cm3

[ Boiling Point ]:
309ºC at 760mmHg

[ Molecular Formula ]:
C11H18N2O2S

[ Molecular Weight ]:
242.34

[ Exact Mass ]:
242.10900

[ PSA ]:
72.71000

[ LogP ]:
1.41810

[ Vapour Pressure ]:
0.000658mmHg at 25°C

[ Index of Refraction ]:
1.56