PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt

Names

[ Name ]:
PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt

[Synonym ]:
PACAP-38 (16-38) (HUMAN,CHICKEN,MOUSE,OVINE,PORCINE,RAT)
H-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2
PACAP (16-38) (HUMAN,OVINE,RAT)
Pituitary Adenylate Cyclase Activating Polypeptide-38 (16-38) (huMan,chicken,Mouse,ovine,porcine,rat)
PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE-38 (16-38),HUMAN,OVINE,RAT
PACAP-38 (16-38),HUMAN,OVINE,RAT
PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE (16-38) (HUMAN,OVINE,RAT)
GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2: QMAVKKYLAAVLGKRYKQRVKNK-NH2

Biological Activity

[Description]:

PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production[1]. PACAP is a potent activator of cAMP formation[2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Braas KM, et al. Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms. Ann N Y Acad Sci. 1996 Dec 26;805:204-16.

[2]. Lania A, et al. Mechanism of action of pituitary adenylate cyclase-activating polypeptide (PACAP) in human nonfunctioning pituitary tumors. J Neuroendocrinol. 1995 Sep;7(9):695-702.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂₃H₂₁₅N₃₉O₂₈S

[ Molecular Weight ]:
2720.33

[ Exact Mass ]:
2718.63000

[ PSA ]:
1184.26000

[ LogP ]:
9.25750