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RS 09

Names

[ CAS No. ]:
1449566-36-2

[ Name ]:
RS 09

[Synonym ]:
L-Alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-L-serine
L-Serine, L-alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-
MFCD30182368

Biological Activity

[Description]:

RS 09 is a TLR4 agonist. RS 09 promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS 09 acts as an adjuvant in vivo; RS 09 enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)
Research Areas >> Inflammation/Immunology

[References]

[1]. Arulkumaran Shanmugam,et al. Synthetic Toll Like receptor-4 (TLR-4) Agonist Peptides as a Novel Class of Adjuvants. PLoS One. 2012;7(2):e30839.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
1191.2±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C31H49N9O9

[ Molecular Weight ]:
691.776

[ Flash Point ]:
674.2±34.3 °C

[ Exact Mass ]:
691.365295

[ LogP ]:
-1.89

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.586

Related Compounds