Z-L-Abu-CONH(CH2)3-morpholine

Names

[ Name ]:
Z-L-Abu-CONH(CH2)3-morpholine

Biological Activity

[Description]:

Calpain Inhibitor XI is a reversible covalent inhibitor of calpain-1. Calpain Inhibitor XI can be used for the research of neurodegenerative disorders[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome

Research Areas >> Neurological Disease

[In Vitro]

Calpain inhibitor XI (CaXI) (1 μM) can inhibit calpain-1, cathepsin-K and also modestly inhibits (∼20%) both papain and cathepsin-B[1].

[References]

[1]. Rachel C Knopp, et al. Extending the Calpain-Cathepsin Hypothesis to the Neurovasculature: Protection of Brain Endothelial Cells and Mice from Neurotrauma. ACS Pharmacol Transl Sci. 2021 Feb 2;4(1):372-385.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₉N₃O₄

[ Molecular Weight ]:
363.45

Z-L-Abu-CONH(CH2)3-morpholine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds