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Orexin receptor antagonist 2

Names

[ CAS No. ]:
1457940-75-8

[ Name ]:
Orexin receptor antagonist 2

Biological Activity

[Description]:

Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Orexin Receptor (OX Receptor)
Research Areas >> Neurological Disease

[References]

[1]. Betschart C, et al. Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia. J Med Chem. 2013;56(19):7590-7607.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H31N5O2

[ Molecular Weight ]:
433.55

Related Compounds