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ZYZ-488

Names

[ CAS No. ]:
1470302-79-4

[ Name ]:
ZYZ-488

Biological Activity

[Description]:

ZYZ-488 is a competitive apoptotic protease activating factor-1 (Apaf-1) inhibitor, which inhibits the activation of binding protein procaspase-9 and procaspase-3[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Apoptosis >> Caspase

[Target]

Apoptotic protease activating factor-1[1]


[References]

[1]. Wang Y, et al. The discovery of a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1) for ischemic heart: synthesis, activity and target identification. Sci Rep. 2016 Jul 22;6:29820.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H29N3O11

[ Molecular Weight ]:
487.46

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds