INO5042

Names

[ CAS No. ]:
14782-19-5

[ Name ]:
INO5042

[Synonym ]:
Naphtho[2,3-d]thiazole-4,9-dione, 2-(2-furanyl)-
2-(2-Furyl)naphtho[2,3-d][1,3]thiazole-4,9-dione

Biological Activity

[Description]:

INO5042 is an anti-inflammatory agent.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[In Vitro]

When INO5042 is added to endothelial cells, a shift of velocities is observed towards fast speeds (from 3-5 to 7-11 microm/sec). The same results is significantly found when neutrophils, alone or along with endothelium, has been submitted to INO5042, the number of stickers and rollers being reduced as well[1].

[References]

[1]. Renard M, et al. Induced changes of leukocyte slow rolling in an in flow pharmacological model of adhesion to endothelial cells. Biorheology. 2003;40(1-3):173-8.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
504.1±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₇NO₃S

[ Molecular Weight ]:
281.286

[ Flash Point ]:
258.7±27.9 °C

[ Exact Mass ]:
281.014648

[ LogP ]:
3.20

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.684

[ Storage condition ]:
2-8℃