IMP2-IN-1

Names

[ CAS No. ]:
1480482-51-6

[ Name ]:
IMP2-IN-1

Biological Activity

[Description]:

IMP2-IN-1 (compound 4) is a potent IMP2 inhibitor with IC50 value of 81.3~127.5 for IMP2 RNA sequence. IMP2-IN-1 reduces IMP2 in SW480 cells. IMP2-IN-1 significantly reduces the viability of both differentiated and non-differentiated Huh7 cells[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

IC50: 81.3~127.5 μM (IMP2)[1]


[References]

[1]. Dahlem C, et al. First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy. ACS Chem Biol. 2022;17(2):361-375.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H14F3NO4

[ Molecular Weight ]:
401.34

Related Compounds