3-Amino-L-alanine hydrochloride

Names

[ Name ]:
3-Amino-L-alanine hydrochloride

[Synonym ]:
Propionic acid, 2,3-diamino-, hydrochloride
UNII:IU6ICR549L
L-(+)-2,3-Diaminopropionic acid hydrochloride
MFCD00065497
ALANINE, 3-AMINO-, MONOHYDROCHLORIDE
H-Dap-OH.HCl
3-Aminoalanine hydrochloride (1:1)
(S)-(+)-2,3-Diaminopropionic Acid Hydrochloride
Alanine, 3-amino-, hydrochloride (1:1)
L(+)-2,3-Diaminopropionic acid hydrochloride
H-Dapa-OH·HCl
(S)-2,3-Diaminopropanoic acid hydrochloride
L-2,3-Amino-L-Alanine HCl
3-Amino-L-alanine hydrochloride

Biological Activity

[Description]:

2,3-Diaminopropionic acid hydrochloride is a competitive inhibitor of cystathionase (CTH)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[Target]

CTH[1].

[References]

[1]. Mushahwar IK, et al. Rat liver L-diaminopropionate ammonia lyase. Identification as cystathionase. J Biol Chem. 1973 Nov 10;248(21):7407-11.

Chemical & Physical Properties

[ Boiling Point ]:
329.9ºC at 760mmHg

[ Melting Point ]:
231-233 °C (dec.)

[ Molecular Formula ]:
C₃H₉ClN₂O₂

[ Molecular Weight ]:
140.57

[ Flash Point ]:
153.3ºC

[ Exact Mass ]:
140.035248

[ PSA ]:
89.34000

[ LogP ]:
0.55960

[ Index of Refraction ]:
24 ° (C=2, 1mol/L HCl)

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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Capreomycin is an important therapeutic agent having intriguing and diverse molecular features. Its polypeptidic structure rich in nitrogen donors makes the drug a promising chelating agent for a numb...

Synthesis of 9-membered dilactams derived from 1,3-diaminopropionic and glutamic acids.

J. Pept. Res. 63(3) , 235-40, (2004)

Previously unknown 9-membered bridged dipeptides derived from l or d isomers of 1,3-diaminopropionic acids and l-glutamic acid were synthesized using aminoacyl incorporation reaction. Key intermediate...