Hydrin 1'

Names

[ Name ]:
Hydrin 1'

[Synonym ]:
H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-GLY-LYS-OH
[Arg8]-Vasotocin-Gly-Lys
(ARG8,GLY10,LYS11)-VASOTOCIN
[ARG8]-VASOTOCIN-GLY-LYS
CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-GLY-LYS

Biological Activity

[Description]:

Hydrin 1′ is found in the neurohypophysis of Xenopus. Hydrin 1′ possesses a considerable steroid-releasing activity in Xenopus adrenal gland in vitro[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Okada R, et al. Arginine vasotocin is the major adrenocorticotropic hormone-releasing factor in the bullfrog Rana catesbeiana. Gen Comp Endocrinol. 2016 Oct 1;237:121-130.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₁H₈₁N₁₇O₁₅S₂

[ Molecular Weight ]:
1236.42

[ Exact Mass ]:
1235.55000

[ PSA ]:
590.46000

[ LogP ]:
1.07550

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Hydrins, hydroosmotic neurohypophysial peptides: osmoregulatory adaptation in amphibians through vasotocin precursor processing.

Proc. Natl. Acad. Sci. U. S. A. 86 , 5272-5275, (1989)

From neurointermediate pituitary glands of Xenopus laevis and Rana esculenta, previously unreported peptides termed hydrins, active on water permeability of frog urinary bladder and frog skin (Brunn o...

Correlation between aquaporin and water permeability in response to vasotocin, hydrin and {beta}-adrenergic effectors in the ventral pelvic skin of the tree frog Hyla japonica.

J. Exp. Biol. 213 , 288-294, (2010)

The ventral pelvic skin of the tree frog Hyla japonica expresses two kinds of arginine vasotocin (AVT)-stimulated aquaporins (AQP-h2 and AQP-h3), which affect the capacity of the frog's skin to absorb...

Molecular cloning of an anuran V(2) type [Arg(8)] vasotocin receptor and mesotocin receptor: functional characterization and tissue expression in the Japanese tree frog (Hyla japonica).

Gen. Comp. Endocrinol. 132 , 485-498, (2003)

In most amphibians, [Arg(8)] vasotocin (VT) has an antidiuretic effect that is coupled to the activation of adenylate cyclase. In contrast, mesotocin (MT) has a diuretic effect and acts via the inosit...