<Suppliers Price>

(S)-WAY 100135

Names

[ CAS No. ]:
149007-54-5

[ Name ]:
(S)-WAY 100135

Biological Activity

[Description]:

(S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[References]

[1]. Cliffe IA, et al. (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. J Med Chem. 1993 May 14;36(10):1509-10.  

Chemical & Physical Properties

[ Molecular Formula ]:
C24H35Cl2N3O2

[ Molecular Weight ]:
468.46

[ Exact Mass ]:
467.21100

[ PSA ]:
48.30000

[ LogP ]:
5.96290

Related Compounds