Phytol

Names

[ CAS No. ]:
150-86-7

[ Name ]:
Phytol

[Synonym ]:
(2E,7R,11R)-3,7,11,15- tetramethyl-2-hexadecen-1-ol
(2E)(7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol
Phytol
3,7,11,15-Tetramethylhexadec-2-en-1-ol
(2E,7R,11R)-3,7,11,15-Tetramethylhexadec-2-en-1-ol
4-01-00-02208 (Beilstein Handbook Reference)
2-Hexadecen-1-ol, 3,7,11,15-tetramethyl-, (2E,7R,11R)-
(2E,7R,11R)-3,7,11,15-Tetramethyl-2-hexadecen-1-ol
(7R,11R,2E)-Phytol
trans-phytol
EINECS 205-776-6
MFCD00151280
(E)-Phytol
Phytol, E-

Biological Activity

[Description]:

Phytol ((E)-Phytol), a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, possesses promising antischistosomal properties. Phytol has antinociceptive and antioxidant activitiesas well as anti-inflammatory and antiallergic effects. Phytol has antimicrobial activity against Mycobacterium tuberculosis and Staphylococcus aureus[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. de Moraes J, et al. Phytol, a diterpene alcohol from chlorophyll, as a drug against neglected tropical diseaseSchistosomiasis mansoni. PLoS Negl Trop Dis. 2014 Jan 2;8(1):e2617.

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
335.5±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₄₀O

[ Molecular Weight ]:
296.531

[ Flash Point ]:
157.5±8.9 °C

[ Exact Mass ]:
296.307922

[ PSA ]:
20.23000

[ LogP ]:
8.66

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.460

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TJ3490000

CHEMICAL NAME :: Phytol

CAS REGISTRY NUMBER :: 150-86-7

BEILSTEIN REFERENCE NO. :: 1726098

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H40-O

MOLECULAR WEIGHT :: 296.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,811,1982 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,811,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,811,1982

Safety Information

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RTECS ]:
TJ3490000

[ HS Code ]:
2905290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2905290000

[ Summary ]:
2905290000 unsaturated monohydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%