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5-Carboxytetramethylrhodamine

Names

[ CAS No. ]:
150322-05-7

[ Name ]:
5-Carboxytetramethylrhodamine

[Synonym ]:
5-carboxy Tamra
5-TAMRA
5-carboxytetramethylrhodamine
Xanthylium, 9-(2,4-dicarboxyphenyl)-3,6-bis(dimethylamino)-, inner salt
2-[3,6-Bis(dimethylamino)-9-xantheniumyl]-5-carboxybenzoate

Biological Activity

[Description]:

5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm[1][2][3].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Lyu Z, et al. Steric-Free Bioorthogonal Labeling of Acetylation Substrates Based on a Fluorine-Thiol Displacement Reaction. J Am Chem Soc. 2021 Jan 27;143(3):1341-1347.

[2]. Bucevičius J, et al. Rhodamine-Hoechst positional isomers for highly efficient staining of heterochromatin. Chem Sci. 2018 Dec 12;10(7):1962-1970.

[3]. Lyttle MH, et al. A tetramethyl rhodamine (Tamra) phosphoramidite facilitates solid-phase-supported synthesis of 5'-Tamra DNA. J Org Chem. 2000 Dec 29;65(26):9033-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H22N2O5

[ Molecular Weight ]:
430.453

[ Exact Mass ]:
430.152863

[ PSA ]:
97.05000

[ LogP ]:
3.72780

Safety Information

[ Safety Phrases ]:
22-24/25

Related Compounds