ETHYL-L-NIO (HYDROCHLORIDE)

Names

[ Name ]:
ETHYL-L-NIO (HYDROCHLORIDE)

[Synonym ]:
Ethyl-L-NIO,hydrochloride

Biological Activity

[Description]:

Ethyl-L-NIO hydrochloride is a potent and competitive human dimethylarginine dimethylaminohydrolase 1 (hDDAH-1) inhibitor with an IC50 of 70 μM and a Ki of 32 μM[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[Target]

IC50: 70 μM (hDDAH-1)[1] Ki: 32 μM (hDDAH-1)[1]

[References]

[1]. Kotthaus J, et al. Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. Bioorg Med Chem. 2008 Dec 15;16(24):10205-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₈ClN₃O₂

[ Molecular Weight ]:
235.71100

[ Exact Mass ]:
235.10900

[ PSA ]:
88.20000

[ LogP ]:
2.34880

ETHYL-L-NIO (HYDROCHLORIDE)

Names

Biological Activity

Chemical & Physical Properties

Related Compounds