AMMONIUM TETRATHIOMOLYBDATE

Names

[ Name ]:
AMMONIUM TETRATHIOMOLYBDATE

[Synonym ]:
Ammonium thiomolybdate Diammonium tetrathiomolybdate
AMMONIUM TETRATHIOMOLYBDATE
diazanium,bis(sulfanylidene)molybdenum,sulfanide
Ammonium tetrathiomolybdate,(trace metal basis)
MFCD00136013

Biological Activity

[Description]:

Ammonium tetrathiomolybdate(VI) is a copper chelator and also is a class of sulfide donor. Ammonium tetrathiomolybdate(VI) has neuroprotection effects. Ammonium tetrathiomolybdate(VI) can be used for the research of brain ischemia[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[In Vivo]

Ammonium tetrathiomolybdate(VI) (ATTM) (i.v.; 10 mg/kg) confers significant neuroprotection[1]. Animal Model: Wistar Rats[1] Dosage: 10 mg/kg Administration: Intravenous Result: Showed improved functional activity at both 24 h and 7-days post-reperfusion, in parallel with a significant reduction in infarct size.

Chemical & Physical Properties

[ Melting Point ]:
>300 °C(lit.)

[ Molecular Formula ]:
H₈MoN₂S₄

[ Molecular Weight ]:
260.29700

[ Exact Mass ]:
261.86200

[ PSA ]:
64.18000

[ LogP ]:
2.04400

[ Storage condition ]:
Refrigerator (+4°C)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
QA4668250

[ HS Code ]:
28417000

Articles

Ion-pair chromatography coupled to inductively coupled plasma-mass spectrometry (IPC-ICP-MS) as a method for thiomolybdate speciation in natural waters.

Anal. Chem. 87(6) , 3388-95, (2015)

Molybdenum precipitates preferentially under reducing conditions; therefore, its occurrence in sediment records is used as an indicator of paleoredox conditions. Although thiomolybdates (MoO4-xSx(2-) ...

Potentiation of antibiofilm activity of amphotericin B by superoxide dismutase inhibition.

Oxid. Med. Cell. Longev. 2013 , 704654, (2013)

This study demonstrates a role for superoxide dismutases (Sods) in governing tolerance of Candida albicans biofilms to amphotericin B (AmB). Coincubation of C. albicans biofilms with AmB and the Sod i...

Regio- and stereospecific synthesis of beta-sulfonamidodisulfides and beta-sulfonamidosulfides from aziridines using tetrathiomolybdate as a sulfur transfer reagent.

J. Org. Chem. 72 , 2106, (2007)

A comprehensive study of a general and effective one-step procedure for the synthesis of beta-sulfonamidodisulfides directly from N-tosyl aziridines in a regio- and stereospecific manner under neutral...