Eosin Y
Names
[ CAS No. ]:
15086-94-9
[ Name ]:
Eosin Y
[Synonym ]:
Bromeosin
D & C Red no. 21
eosine acid
eosine lactonique
Benzoic acid, 2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, sodium salt (1:2)
TetrabroMofluorescein
C.I. Solvent Red 43
MFCD00036189
D and C Red No. 21
Eosin Y alcohol
Japan Red 223
eosin yellowish
2',4',5',7'-Tetrabromofluorescein
eosin yellow
Bromoeosin
EINECS 239-138-3
Solvent Red 43
Disodium 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
2',4',5',7'-tetrabromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
Eosin acid
Eosine Yellowish-(YS)
2,4,5,7-tetrabromofluorescein
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.02 g/mL at 20ºC
[ Boiling Point ]:
640.3ºC at 760 mmHg
[ Melting Point ]:
295ºC
[ Molecular Formula ]:
C20H8Br4O5
[ Molecular Weight ]:
691.854
[ Exact Mass ]:
687.674377
[ PSA ]:
93.40000
[ LogP ]:
6.12210
[ Index of Refraction ]:
1.757
[ Stability ]:
Stable. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
H2O: 0.1 g/mL, dark red
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LM5800000
- CHEMICAL NAME :
- Fluorescein, 2',4',5',7'-tetrabromo-
- CAS REGISTRY NUMBER :
- 15086-94-9
- BEILSTEIN REFERENCE NO. :
- 0063410
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C20-H8-Br4-O5
- MOLECULAR WEIGHT :
- 647.92
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA repair
- TEST SYSTEM :
- Bacteria - Bacillus subtilis
- DOSE/DURATION :
- 2 mg/disc
- REFERENCE :
- TRENAF Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. (Tokyo-toritsu Eisei Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50- Volume(issue)/page/year: 27,153,1976 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,183,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,183,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0363 No. of Facilities: 347 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 7340 (estimated) No. of Female Employees: 1584 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36
[ Safety Phrases ]:
26
[ RIDADR ]:
UN 1170 3/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
LM5850000
[ HS Code ]:
32041919
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Gastroenterology 147(6) , 1405-16.e7, (2014)
New drug targets are urgently needed for the treatment of patients with pancreatic ductal adenocarcinoma (PDA). Nearly all PDAs contain oncogenic mutations in the KRAS gene. Pharmacological inhibition...
Chondrogenesis of human bone marrow mesenchymal stromal cells in highly porous alginate-foams supplemented with chondroitin sulfate.Mater. Sci. Eng. C. Mater. Biol. Appl. 50 , 160-72, (2015)
To overcome the limited intrinsic cartilage repair, autologous chondrocyte or bone-marrow-derived mesenchymal stromal cell (BM-MSC) was implanted into cartilage defects. For this purpose suitable bioc...
Enhanced antitumor effects of the BRBP1 compound peptide BRBP1-TAT-KLA on human brain metastatic breast cancer.Sci. Rep. 5 , 8029, (2015)
Novel molecularly targeted agents that block the development and metastasis of human brain metastatic breast cancer hold great promise for their translational value. In this study, we constructed a no...